Experimental Models in Neurodegenerative Diseases
نویسندگان
چکیده
منابع مشابه
Animal models in neurodegenerative diseases.
Ideally, animal models of neurodegenerative diseases should reproduce the clinical manifestation of the disease and a selective neuronal loss. In this review we will take as an example Parkinson's disease because its pathophysiology is well known and the neuronal loss well characterized. Indeed, Parkinson's disease is characterized by a loss of some but not all dopaminergic neurons, a loss of s...
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The prevalence of neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), increases with age, and the number of affected patients is expected to increase worldwide in the next decades. Accurately understanding the etiopathogenic mechanisms of these diseases is a crucial step for developing disease-modifying drugs able to preclude their emergence or at least sl...
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ژورنال
عنوان ژورنال: Nuclear Medicine Seminars
سال: 2019
ISSN: 2149-6447
DOI: 10.4274/nts.galenos.2019.0009